Enhanced Responses to Angiogenic Cues Underlie the Pathogenesis of Hereditary Hemorrhagic Telangiectasia 2

Hereditary Hemorrhagic Telangiectasia (HHT) is a genetic vascular disease in which arteriovenous malformations (AVMs) manifest in skin and multiple visceral organs. HHT is caused by heterozygous mutations in endoglin (ENG), activin receptor-like kinase 1 (ALK1), or SMAD4. ALK1 regulates angiogenesis...

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Detalles Bibliográficos
Autores principales: Choi, Eun-Jung, Kim, Yong Hwan, Choe, Se-woon, Tak, Yu Gyoung, Garrido-Martin, Eva M., Chang, Myron, Lee, Young Jae, Oh, S. Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651154/
https://www.ncbi.nlm.nih.gov/pubmed/23675457
http://dx.doi.org/10.1371/journal.pone.0063138

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