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Fine-Mapping and Genetic Analysis of the Loci Affecting Hepatic Iron Overload in Mice

The liver, as the major organ for iron storage and production of hepcidin, plays pivotal roles in maintaining mammalian iron homeostasis. A previous study showed that Quantitative Trait Loci (QTLs) on chromosome 7 (Chr7) and 16 (Chr16) may control hepatic non-heme iron overload in an F2 intercross d...

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Detalles Bibliográficos
Autores principales:	Guo, Xin, Zhang, Zhuzhen, Zhang, Fan, Tao, Yunlong, An, Peng, Wu, Qian, Wang, Chia-Yu, Knutson, Mitchell D., Wang, Fudi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651197/ https://www.ncbi.nlm.nih.gov/pubmed/23675470 http://dx.doi.org/10.1371/journal.pone.0063280

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