Human marrow stromal cells reduce microglial activation to protect motor neurons in a transgenic mouse model of amyotrophic lateral sclerosis

BACKGROUND: Human marrow stromal cells (hMSCs) injected intrathecally can effectively increase the lifespan and protect motor neurons in a transgenic mouse model of amyotrophic lateral sclerosis. However, how the transplanted cells exert a neuroprotective effect is still unclear. More recently, the...

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Detalles Bibliográficos
Autores principales: Zhou, Chang, Zhang, Chen, Zhao, Renliang, Chi, Song, Ge, Ping, Zhang, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651332/
https://www.ncbi.nlm.nih.gov/pubmed/23631660
http://dx.doi.org/10.1186/1742-2094-10-52

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