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The 0.3-kb fragment containing the R-U5-5’leader sequence of Friend murine leukemia virus influences the level of protein expression from spliced mRNA

BACKGROUND: A neuropathogenic variant of Friend murine leukemia virus (Fr-MLV) clone A8 induces spongiform neurodegeneration when infected into neonatal rats. Studies with chimeras constructed from the A8 virus and the non-neuropathogenic Fr-MLV clone 57 identified a 0.3-kb KpnI-AatII fragment conta...

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Detalles Bibliográficos
Autores principales: Choo, Yeng Cheng, Seki, Yohei, Machinaga, Akihito, Ogita, Nobuo, Takase-Yoden, Sayaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651342/
https://www.ncbi.nlm.nih.gov/pubmed/23602143
http://dx.doi.org/10.1186/1743-422X-10-124