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Lipid-lowering fibrates extend C. elegans lifespan in a NHR-49/PPARalpha-dependent manner
Compounds that delay aging in model organisms may be of significant interest to anti-aging medicine, since these substances potentially provide pharmaceutical approaches to promote healthy lifespan in humans. We here aimed to test whether pharmaceutical concentrations of three fibrates, pharmacologi...
Autores principales: | Brandstädt, Sven, Schmeisser, Kathrin, Zarse, Kim, Ristow, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651519/ https://www.ncbi.nlm.nih.gov/pubmed/23603800 |
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