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From evidence based medicine to mechanism based medicine. Reviewing the role of pharmacogenetics
Aim of the review The translation of evidence based medicine to a specific patient presents a considerable challenge. We present by means of the examples nortriptyline, tramadol, clopidogrel, coumarins, abacavir and antipsychotics the discrepancy between available pharmacogenetic information and its...
Autores principales: | Wilffert, Bob, Swen, Jesse, Mulder, Hans, Touw, Daan, Maitland-Van der Zee, Anke-Hilse, Deneer, Vera |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651527/ https://www.ncbi.nlm.nih.gov/pubmed/21049305 http://dx.doi.org/10.1007/s11096-010-9446-1 |
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