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From evidence based medicine to mechanism based medicine. Reviewing the role of pharmacogenetics

Aim of the review The translation of evidence based medicine to a specific patient presents a considerable challenge. We present by means of the examples nortriptyline, tramadol, clopidogrel, coumarins, abacavir and antipsychotics the discrepancy between available pharmacogenetic information and its...

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Detalles Bibliográficos
Autores principales: Wilffert, Bob, Swen, Jesse, Mulder, Hans, Touw, Daan, Maitland-Van der Zee, Anke-Hilse, Deneer, Vera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651527/
https://www.ncbi.nlm.nih.gov/pubmed/21049305
http://dx.doi.org/10.1007/s11096-010-9446-1

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