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Tolerance to MHC class II disparate allografts through genetic modification of bone marrow
Induction of molecular chimerism through genetic modification of bone marrow is a powerful tool for the induction of tolerance. Here we demonstrate for the first time that expression of an allogeneic MHC class II gene in autologous bone marrow cells, resulting in a state of molecular chimerism, indu...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651743/ https://www.ncbi.nlm.nih.gov/pubmed/22833118 http://dx.doi.org/10.1038/gt.2012.57 |