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RNA Tertiary Interactions in a Riboswitch Stabilize the Structure of a Kink Turn

The kink turn is a widespread RNA motif that introduces an acute kink into the axis of duplex RNA, typically comprising a bulge followed by a G⋅A and A⋅G pairs. The kinked conformation is stabilized by metal ions, or the binding of proteins including L7Ae. We now demonstrate a third mechanism for th...

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Detalles Bibliográficos
Autores principales: Schroeder, Kersten T., Daldrop, Peter, Lilley, David M.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651934/
https://www.ncbi.nlm.nih.gov/pubmed/21893284
http://dx.doi.org/10.1016/j.str.2011.07.003