Small-Sized Clone of T Cells in Multiple Myeloma Patient after Auto-SCT: T-LGL Leukemia Type or Clonal T-Cell Aberration?

Second cancers and particularly postransplant lymphoproliferative disorders (PTLDs) are extremely rare in patients undergoing autologous peripheral blood stem cell transplantation (auto-SCT). We report the case of clonally rearranged T-cell expansion which occurred after auto-SCT for Multiple Myelom...

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Autores principales: Mele, Giuseppe, Greco, Marilena, Coppi, Maria Rosaria, Loseto, Giacomo, Melpignano, Angela, Mauro, Salvatore, Quarta, Gianni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652047/
https://www.ncbi.nlm.nih.gov/pubmed/23691376
http://dx.doi.org/10.1155/2013/417353
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author Mele, Giuseppe
Greco, Marilena
Coppi, Maria Rosaria
Loseto, Giacomo
Melpignano, Angela
Mauro, Salvatore
Quarta, Gianni
author_facet Mele, Giuseppe
Greco, Marilena
Coppi, Maria Rosaria
Loseto, Giacomo
Melpignano, Angela
Mauro, Salvatore
Quarta, Gianni
author_sort Mele, Giuseppe
collection PubMed
description Second cancers and particularly postransplant lymphoproliferative disorders (PTLDs) are extremely rare in patients undergoing autologous peripheral blood stem cell transplantation (auto-SCT). We report the case of clonally rearranged T-cell expansion which occurred after auto-SCT for Multiple Myeloma (MM). Does asymptomatic clonal T-cell large granular lymphocytic proliferation, in our experience, represent either a secondary cancer after auto-SCT or clonal T cell aberration or derive from expansion of coexisting undetected small-sized clone of T cells?
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spelling pubmed-36520472013-05-20 Small-Sized Clone of T Cells in Multiple Myeloma Patient after Auto-SCT: T-LGL Leukemia Type or Clonal T-Cell Aberration? Mele, Giuseppe Greco, Marilena Coppi, Maria Rosaria Loseto, Giacomo Melpignano, Angela Mauro, Salvatore Quarta, Gianni Case Rep Hematol Case Report Second cancers and particularly postransplant lymphoproliferative disorders (PTLDs) are extremely rare in patients undergoing autologous peripheral blood stem cell transplantation (auto-SCT). We report the case of clonally rearranged T-cell expansion which occurred after auto-SCT for Multiple Myeloma (MM). Does asymptomatic clonal T-cell large granular lymphocytic proliferation, in our experience, represent either a secondary cancer after auto-SCT or clonal T cell aberration or derive from expansion of coexisting undetected small-sized clone of T cells? Hindawi Publishing Corporation 2013 2013-04-21 /pmc/articles/PMC3652047/ /pubmed/23691376 http://dx.doi.org/10.1155/2013/417353 Text en Copyright © 2013 Giuseppe Mele et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Mele, Giuseppe
Greco, Marilena
Coppi, Maria Rosaria
Loseto, Giacomo
Melpignano, Angela
Mauro, Salvatore
Quarta, Gianni
Small-Sized Clone of T Cells in Multiple Myeloma Patient after Auto-SCT: T-LGL Leukemia Type or Clonal T-Cell Aberration?
title Small-Sized Clone of T Cells in Multiple Myeloma Patient after Auto-SCT: T-LGL Leukemia Type or Clonal T-Cell Aberration?
title_full Small-Sized Clone of T Cells in Multiple Myeloma Patient after Auto-SCT: T-LGL Leukemia Type or Clonal T-Cell Aberration?
title_fullStr Small-Sized Clone of T Cells in Multiple Myeloma Patient after Auto-SCT: T-LGL Leukemia Type or Clonal T-Cell Aberration?
title_full_unstemmed Small-Sized Clone of T Cells in Multiple Myeloma Patient after Auto-SCT: T-LGL Leukemia Type or Clonal T-Cell Aberration?
title_short Small-Sized Clone of T Cells in Multiple Myeloma Patient after Auto-SCT: T-LGL Leukemia Type or Clonal T-Cell Aberration?
title_sort small-sized clone of t cells in multiple myeloma patient after auto-sct: t-lgl leukemia type or clonal t-cell aberration?
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652047/
https://www.ncbi.nlm.nih.gov/pubmed/23691376
http://dx.doi.org/10.1155/2013/417353
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