Cargando…
Improved adeno-associated virus (AAV) serotype 1 and 5 vectors for gene therapy
Despite significant advancements with recombinant AAV2 or AAV8 vectors for liver directed gene therapy in humans, it is well-recognized that host and vector-related immune challenges need to be overcome for long-term gene transfer. To overcome these limitations, alternate AAV serotypes (1–10) are be...
Autores principales: | Sen, Dwaipayan, Balakrishnan, Balaji, Gabriel, Nishanth, Agrawal, Prachi, Roshini, Vaani, Samuel, Rekha, Srivastava, Alok, Jayandharan, Giridhara R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652085/ https://www.ncbi.nlm.nih.gov/pubmed/23665951 http://dx.doi.org/10.1038/srep01832 |
Ejemplares similares
-
Activation of the Cellular Unfolded Protein Response by Recombinant Adeno-Associated Virus Vectors
por: Balakrishnan, Balaji, et al.
Publicado: (2013) -
Infectivity of adeno-associated virus serotypes in mouse testis
por: Rajasekaran, Santhanasabapathy, et al.
Publicado: (2018) -
Post‐translational modifications in capsid proteins of recombinant adeno‐associated virus (AAV) 1‐rh10 serotypes
por: Mary, Bertin, et al.
Publicado: (2019) -
Cellular unfolded protein response against viruses used in gene therapy
por: Sen, Dwaipayan, et al.
Publicado: (2014) -
Innate Immune Responses to AAV Vectors
por: Rogers, Geoffrey L., et al.
Publicado: (2011)