Role of M2 Muscarinic Receptor in the Airway Response to Methacholine of Mice Selected for Minimal or Maximal Acute Inflammatory Response

Airway smooth muscle constriction induced by cholinergic agonists such as methacholine (MCh), which is typically increased in asthmatic patients, is regulated mainly by muscle muscarinic M3 receptors and negatively by vagal muscarinic M2 receptors. Here we evaluated basal (intrinsic) and allergen-in...

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Detalles Bibliográficos
Autores principales: Castro, Juciane Maria de Andrade, Resende, Rodrigo R., Mirotti, Luciana, Florsheim, Esther, Albuquerque, Layra Lucy, Lino-dos-Santos-Franco, Adriana, Gomes, Eliane, Tavares de Lima, Wothan, de Franco, Marcelo, Ribeiro, Orlando Garcia, Russo, Momtchilo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652127/
https://www.ncbi.nlm.nih.gov/pubmed/23691511
http://dx.doi.org/10.1155/2013/805627

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