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Obesity and Inflammation: Epidemiology, Risk Factors, and Markers of Inflammation
Obesity is a public health problem that has reached epidemic proportions with an increasing worldwide prevalence. The global emergence of obesity increases the risk of developing chronic metabolic disorders. Thus, it is an economic issue that increased the costs of the comorbidities associated. More...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652163/ https://www.ncbi.nlm.nih.gov/pubmed/23690772 http://dx.doi.org/10.1155/2013/678159 |
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author | Rodríguez-Hernández, Heriberto Simental-Mendía, Luis E. Rodríguez-Ramírez, Gabriela Reyes-Romero, Miguel A. |
author_facet | Rodríguez-Hernández, Heriberto Simental-Mendía, Luis E. Rodríguez-Ramírez, Gabriela Reyes-Romero, Miguel A. |
author_sort | Rodríguez-Hernández, Heriberto |
collection | PubMed |
description | Obesity is a public health problem that has reached epidemic proportions with an increasing worldwide prevalence. The global emergence of obesity increases the risk of developing chronic metabolic disorders. Thus, it is an economic issue that increased the costs of the comorbidities associated. Moreover, in recent years, it has been demonstrated that obesity is associated with chronic systemic inflammation, this status is conditioned by the innate immune system activation in adipose tissue that promotes an increase in the production and release of pro-inflammatory cytokines that contribute to the triggering of the systemic acute-phase response which is characterized by elevation of acute-phase protein levels. On this regard, low-grade chronic inflammation is a characteristic of various chronic diseases such as metabolic syndrome, cardiovascular disease, diabetes, hypertension, non-alcoholic fatty liver disease, and some cancers, among others, which are also characterized by obesity condition. Thus, a growing body of evidence supports the important role that is played by the inflammatory response in obesity condition and the pathogenesis of chronic diseases related. |
format | Online Article Text |
id | pubmed-3652163 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-36521632013-05-20 Obesity and Inflammation: Epidemiology, Risk Factors, and Markers of Inflammation Rodríguez-Hernández, Heriberto Simental-Mendía, Luis E. Rodríguez-Ramírez, Gabriela Reyes-Romero, Miguel A. Int J Endocrinol Review Article Obesity is a public health problem that has reached epidemic proportions with an increasing worldwide prevalence. The global emergence of obesity increases the risk of developing chronic metabolic disorders. Thus, it is an economic issue that increased the costs of the comorbidities associated. Moreover, in recent years, it has been demonstrated that obesity is associated with chronic systemic inflammation, this status is conditioned by the innate immune system activation in adipose tissue that promotes an increase in the production and release of pro-inflammatory cytokines that contribute to the triggering of the systemic acute-phase response which is characterized by elevation of acute-phase protein levels. On this regard, low-grade chronic inflammation is a characteristic of various chronic diseases such as metabolic syndrome, cardiovascular disease, diabetes, hypertension, non-alcoholic fatty liver disease, and some cancers, among others, which are also characterized by obesity condition. Thus, a growing body of evidence supports the important role that is played by the inflammatory response in obesity condition and the pathogenesis of chronic diseases related. Hindawi Publishing Corporation 2013 2013-04-17 /pmc/articles/PMC3652163/ /pubmed/23690772 http://dx.doi.org/10.1155/2013/678159 Text en Copyright © 2013 Heriberto Rodríguez-Hernández et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Rodríguez-Hernández, Heriberto Simental-Mendía, Luis E. Rodríguez-Ramírez, Gabriela Reyes-Romero, Miguel A. Obesity and Inflammation: Epidemiology, Risk Factors, and Markers of Inflammation |
title | Obesity and Inflammation: Epidemiology, Risk Factors, and Markers of Inflammation |
title_full | Obesity and Inflammation: Epidemiology, Risk Factors, and Markers of Inflammation |
title_fullStr | Obesity and Inflammation: Epidemiology, Risk Factors, and Markers of Inflammation |
title_full_unstemmed | Obesity and Inflammation: Epidemiology, Risk Factors, and Markers of Inflammation |
title_short | Obesity and Inflammation: Epidemiology, Risk Factors, and Markers of Inflammation |
title_sort | obesity and inflammation: epidemiology, risk factors, and markers of inflammation |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652163/ https://www.ncbi.nlm.nih.gov/pubmed/23690772 http://dx.doi.org/10.1155/2013/678159 |
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