Cargando…

Obesity and Inflammation: Epidemiology, Risk Factors, and Markers of Inflammation

Obesity is a public health problem that has reached epidemic proportions with an increasing worldwide prevalence. The global emergence of obesity increases the risk of developing chronic metabolic disorders. Thus, it is an economic issue that increased the costs of the comorbidities associated. More...

Descripción completa

Detalles Bibliográficos
Autores principales: Rodríguez-Hernández, Heriberto, Simental-Mendía, Luis E., Rodríguez-Ramírez, Gabriela, Reyes-Romero, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652163/
https://www.ncbi.nlm.nih.gov/pubmed/23690772
http://dx.doi.org/10.1155/2013/678159
_version_ 1782269288496758784
author Rodríguez-Hernández, Heriberto
Simental-Mendía, Luis E.
Rodríguez-Ramírez, Gabriela
Reyes-Romero, Miguel A.
author_facet Rodríguez-Hernández, Heriberto
Simental-Mendía, Luis E.
Rodríguez-Ramírez, Gabriela
Reyes-Romero, Miguel A.
author_sort Rodríguez-Hernández, Heriberto
collection PubMed
description Obesity is a public health problem that has reached epidemic proportions with an increasing worldwide prevalence. The global emergence of obesity increases the risk of developing chronic metabolic disorders. Thus, it is an economic issue that increased the costs of the comorbidities associated. Moreover, in recent years, it has been demonstrated that obesity is associated with chronic systemic inflammation, this status is conditioned by the innate immune system activation in adipose tissue that promotes an increase in the production and release of pro-inflammatory cytokines that contribute to the triggering of the systemic acute-phase response which is characterized by elevation of acute-phase protein levels. On this regard, low-grade chronic inflammation is a characteristic of various chronic diseases such as metabolic syndrome, cardiovascular disease, diabetes, hypertension, non-alcoholic fatty liver disease, and some cancers, among others, which are also characterized by obesity condition. Thus, a growing body of evidence supports the important role that is played by the inflammatory response in obesity condition and the pathogenesis of chronic diseases related.
format Online
Article
Text
id pubmed-3652163
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-36521632013-05-20 Obesity and Inflammation: Epidemiology, Risk Factors, and Markers of Inflammation Rodríguez-Hernández, Heriberto Simental-Mendía, Luis E. Rodríguez-Ramírez, Gabriela Reyes-Romero, Miguel A. Int J Endocrinol Review Article Obesity is a public health problem that has reached epidemic proportions with an increasing worldwide prevalence. The global emergence of obesity increases the risk of developing chronic metabolic disorders. Thus, it is an economic issue that increased the costs of the comorbidities associated. Moreover, in recent years, it has been demonstrated that obesity is associated with chronic systemic inflammation, this status is conditioned by the innate immune system activation in adipose tissue that promotes an increase in the production and release of pro-inflammatory cytokines that contribute to the triggering of the systemic acute-phase response which is characterized by elevation of acute-phase protein levels. On this regard, low-grade chronic inflammation is a characteristic of various chronic diseases such as metabolic syndrome, cardiovascular disease, diabetes, hypertension, non-alcoholic fatty liver disease, and some cancers, among others, which are also characterized by obesity condition. Thus, a growing body of evidence supports the important role that is played by the inflammatory response in obesity condition and the pathogenesis of chronic diseases related. Hindawi Publishing Corporation 2013 2013-04-17 /pmc/articles/PMC3652163/ /pubmed/23690772 http://dx.doi.org/10.1155/2013/678159 Text en Copyright © 2013 Heriberto Rodríguez-Hernández et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Rodríguez-Hernández, Heriberto
Simental-Mendía, Luis E.
Rodríguez-Ramírez, Gabriela
Reyes-Romero, Miguel A.
Obesity and Inflammation: Epidemiology, Risk Factors, and Markers of Inflammation
title Obesity and Inflammation: Epidemiology, Risk Factors, and Markers of Inflammation
title_full Obesity and Inflammation: Epidemiology, Risk Factors, and Markers of Inflammation
title_fullStr Obesity and Inflammation: Epidemiology, Risk Factors, and Markers of Inflammation
title_full_unstemmed Obesity and Inflammation: Epidemiology, Risk Factors, and Markers of Inflammation
title_short Obesity and Inflammation: Epidemiology, Risk Factors, and Markers of Inflammation
title_sort obesity and inflammation: epidemiology, risk factors, and markers of inflammation
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652163/
https://www.ncbi.nlm.nih.gov/pubmed/23690772
http://dx.doi.org/10.1155/2013/678159
work_keys_str_mv AT rodriguezhernandezheriberto obesityandinflammationepidemiologyriskfactorsandmarkersofinflammation
AT simentalmendialuise obesityandinflammationepidemiologyriskfactorsandmarkersofinflammation
AT rodriguezramirezgabriela obesityandinflammationepidemiologyriskfactorsandmarkersofinflammation
AT reyesromeromiguela obesityandinflammationepidemiologyriskfactorsandmarkersofinflammation