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Epileptogenic Q555X SYN1 mutant triggers imbalances in release dynamics and short-term plasticity

Synapsin I (SynI) is a synaptic vesicle (SV) phosphoprotein playing multiple roles in synaptic transmission and plasticity by differentially affecting crucial steps of SV trafficking in excitatory and inhibitory synapses. SynI knockout (KO) mice are epileptic, and nonsense and missense mutations in...

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Detalles Bibliográficos
Autores principales:	Lignani, Gabriele, Raimondi, Andrea, Ferrea, Enrico, Rocchi, Anna, Paonessa, Francesco, Cesca, Fabrizia, Orlando, Marta, Tkatch, Tatiana, Valtorta, Flavia, Cossette, Patrick, Baldelli, Pietro, Benfenati, Fabio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652419/ https://www.ncbi.nlm.nih.gov/pubmed/23406870 http://dx.doi.org/10.1093/hmg/ddt071

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