Cargando…

The sterol regulatory element binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity

Newly activated CD8(+) T cells reprogram their metabolism to meet the extraordinary biosynthetic demands of clonal expansion; however, the signals mediating metabolic reprogramming remain poorly defined. Herein, we demonstrate an essential role for sterol regulatory element binding proteins (SREBPs)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kidani, Yoko, Elsaesser, Heidi, Hock, M Benjamin, Vergnes, Laurent, Williams, Kevin J, Argus, Joseph P, Marbois, Beth N, Komisopoulou, Evangelia, Wilson, Elizabeth B, Osborne, Timothy F, Graeber, Thomas G, Reue, Karen, Brooks, David G, Bensinger, Steven J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652626/ https://www.ncbi.nlm.nih.gov/pubmed/23563690 http://dx.doi.org/10.1038/ni.2570

Ejemplares similares

Phosphoproteomic Analysis of Platelets Activated by Pro-Thrombotic Oxidized Phospholipids and Thrombin
por: Zimman, Alejandro, et al.
Publicado: (2014)

Adaptive Thermogenesis in White Adipose Tissue: Is Lactate the New Brown(ing)?
por: Vergnes, Laurent, et al.
Publicado: (2014)

Subverting sterols: rerouting an oxysterol-signaling pathway to promote tumor growth
por: York, Autumn G., et al.
Publicado: (2013)

Sterol Regulatory Element-Binding Protein (Sre1) Promotes the Synthesis of Carotenoids and Sterols in Xanthophyllomyces dendrorhous
por: Gutiérrez, María Soledad, et al.
Publicado: (2019)

Effects of sterol regulatory element-binding protein (SREBP) in chickens
por: Alipour, Fahimeh, et al.
Publicado: (2012)

Role of the Sterol Regulatory Element Binding Protein Pathway in Tumorigenesis
por: Jiang, Tao, et al.
Publicado: (2020)

Essentiality of sterol synthesis genes in the planctomycete bacterium Gemmata obscuriglobus
por: Rivas-Marin, Elena, et al.
Publicado: (2019)

MicroRNA-21 targets the vitamin D-dependent antimicrobial pathway in leprosy
por: Liu, Philip T., et al.
Publicado: (2012)

Glucose deprivation activates a metabolic and signaling amplification loop leading to cell death
por: Graham, Nicholas A, et al.
Publicado: (2012)

The SREBP (Sterol Regulatory Element-Binding Protein) pathway: a regulatory bridge between carotenogenesis and sterol biosynthesis in the carotenogenic yeast Xanthophyllomyces dendrorhous
por: Gómez, Melissa, et al.
Publicado: (2021)

A mathematical model of the sterol regulatory element binding protein 2 cholesterol biosynthesis pathway
por: Bhattacharya, Bonhi S., et al.
Publicado: (2014)

Metformin induces distinct bioenergetic and metabolic profiles in sensitive versus resistant high grade serous ovarian cancer and normal fallopian tube secretory epithelial cells
por: Hodeib, Melissa, et al.
Publicado: (2017)

Functional analysis of two sterol regulatory element binding proteins in Penicillium digitatum
por: Ruan, Ruoxin, et al.
Publicado: (2017)

Targeting Ergosterol Biosynthesis in Leishmania donovani: Essentiality of Sterol 14alpha-demethylase
por: McCall, Laura-Isobel, et al.
Publicado: (2015)

Perilipin-Mediated Lipid Droplet Formation in Adipocytes Promotes Sterol Regulatory Element-Binding Protein-1 Processing and Triacylglyceride Accumulation
por: Takahashi, Yu, et al.
Publicado: (2013)

Insulin‐dependent and ‐independent regulation of sterol regulatory element‐binding protein‐1c
por: Matsuzaka, Takashi, et al.
Publicado: (2013)

Activation of Sterol Regulatory Element Binding Factors by Fenofibrate and Gemfibrozil Stimulates Myelination in Zebrafish
por: Ashikawa, Yoshifumi, et al.
Publicado: (2016)

Sterol regulatory element binding protein 1 couples mechanical cues and lipid metabolism
por: Bertolio, Rebecca, et al.
Publicado: (2019)

Average Shear Rates in the Screw Elements of a Corotating Twin-Screw Extruder
por: Vergnes, Bruno
Publicado: (2021)

Heterocyclic sterol probes for live monitoring of sterol trafficking and lysosomal storage disorders
por: Králová, Jarmila, et al.
Publicado: (2018)

A sterol-defined system for quantitative studies of sterol metabolism in C. elegans
por: Trabelcy, Benjamin, et al.
Publicado: (2021)

Simultaneous monitoring of mouse grip strength, force profile, and cumulative force profile distinguishes muscle physiology following surgical, pharmacologic and diet interventions
por: Munier, Joseph J., et al.
Publicado: (2022)

Sterol Regulatory Element-Binding Proteins Are Regulators of the Rat Thyroid Peroxidase Gene in Thyroid Cells
por: Rauer, Christine, et al.
Publicado: (2014)

MicroRNA-33 regulates sterol regulatory element-binding protein 1 expression in mice
por: Horie, Takahiro, et al.
Publicado: (2013)

Increased expression of sterol regulatory element binding protein-2 alleviates autophagic dysfunction in NAFLD
por: Cheng, Chunwei, et al.
Publicado: (2018)

Dysregulation of sterol regulatory element-binding protein 2 gene in HIV treatment-experienced individuals
por: Sopeyin, Anuoluwapo, et al.
Publicado: (2019)

TDP-43 regulates cholesterol biosynthesis by inhibiting sterol regulatory element-binding protein 2
por: Egawa, Naohiro, et al.
Publicado: (2022)

The Peroxisomal Targeting Signal 1 in sterol carrier protein 2 is autonomous and essential for receptor recognition
por: Williams, Chris P, et al.
Publicado: (2011)

The sterol C-24 methyltransferase encoding gene, erg6, is essential for viability of Aspergillus species
por: Xie, Jinhong, et al.
Publicado: (2023)

JUN dependency in distinct early and late BRAF inhibition adaptation states of melanoma
por: Titz, Bjoern, et al.
Publicado: (2016)

A Reappraisal of the Mechanism by Which Plant Sterols Promote Neutral Sterol Loss in Mice
por: Brufau, Gemma, et al.
Publicado: (2011)

Interactions of antiparasitic sterols with sterol 14α-demethylase (CYP51) of human pathogens
por: Warfield, Jasmine, et al.
Publicado: (2014)

Comparative interactions of withanolides and sterols with two members of sterol glycosyltransferases from Withania somnifera
por: Pandey, Vibha, et al.
Publicado: (2015)

Exchange of water for sterol underlies sterol egress from a StARkin domain
por: Khelashvili, George, et al.
Publicado: (2019)

Diversity of Plant Sterols Metabolism: The Impact on Human Health, Sport, and Accumulation of Contaminating Sterols
por: Kopylov, Arthur T., et al.
Publicado: (2021)

Sterol biosensor reveals LAM-family Ltc1-dependent sterol flow to endosomes upon Arp2/3 inhibition
por: Marek, Magdalena, et al.
Publicado: (2020)

The Interaction of Dipole Modifiers with Polyene-Sterol Complexes
por: Ostroumova, Olga S., et al.
Publicado: (2012)

Sterol-Sensing Domain (SSD)-Containing Proteins in Sterol Auxotrophic Phytophthora capsici Mediate Sterol Signaling and Play a Role in Asexual Reproduction and Pathogenicity
por: Wang, Weizhen, et al.
Publicado: (2023)

Sulforaphane suppresses the activity of sterol regulatory element-binding proteins (SREBPs) by promoting SREBP precursor degradation
por: Miyata, Shingo, et al.
Publicado: (2022)

ELECTROPHORESIS OF STEROLS : II. ERGOSTEROL
por: Moyer, Laurence S.
Publicado: (1935)

Cannot write session to /tmp/vufind_sessions/sess_kfa0p22kigirt3u7h4s4qjmj90