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Acetylcholineestarase-Inhibiting Alkaloids from Lycoris radiata Delay Paralysis of Amyloid Beta-Expressing Transgenic C. elegans CL4176
The limited symptom relief and side effects of current Alzheimer’s disease (AD) medications warrant urgent discovery and study of new anti-AD agents. The “cholinergic hypothesis” of AD prompts us to search for plant-derived acetylcholineesterase (AChE) inhibitors such as galanthamine that has been l...
Autores principales: | Xin, Lijuan, Yamujala, Ritupriya, Wang, Yuehu, Wang, Huan, Wu, Wen-Hsuan, Lawton, Michael A., Long, Chunlin, Di, Rong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652842/ https://www.ncbi.nlm.nih.gov/pubmed/23675513 http://dx.doi.org/10.1371/journal.pone.0063874 |
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