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Peroxisome Proliferator-Activated Receptor (PPAR) γ and PPARα Agonists Modulate Mitochondrial Fusion-Fission Dynamics: Relevance to Reactive Oxygen Species (ROS)-Related Neurodegenerative Disorders?

Recent studies showed that the activation of the retinoid X receptor, which dimerizes with peroxisome proliferator-activated receptors (PPARs), leads to an enhanced clearance of Aβ from the brain of transgenic mice model of Alzheimer’s disease (AD), because an increased expression of apolipoprotein...

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Detalles Bibliográficos
Autores principales: Zolezzi, Juan M., Silva-Alvarez, Carmen, Ordenes, Daniela, Godoy, Juan A., Carvajal, Francisco J., Santos, Manuel J., Inestrosa, Nibaldo C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652852/
https://www.ncbi.nlm.nih.gov/pubmed/23675519
http://dx.doi.org/10.1371/journal.pone.0064019

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