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TRIM11 Negatively Regulates IFNβ Production and Antiviral Activity by Targeting TBK1
The innate immune response is a host defense mechanism against infection by viruses and bacteria. Type I interferons (IFNα/β) play a crucial role in innate immunity. If not tightly regulated under normal conditions and during immune responses, IFN production can become aberrant, leading to inflammat...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652858/ https://www.ncbi.nlm.nih.gov/pubmed/23675467 http://dx.doi.org/10.1371/journal.pone.0063255 |