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Targeted disruption of glutathione peroxidase 4 (GPx4) in mouse skin epithelial cells impairs postnatal hair follicle morphogenesis that is partially rescued through inhibition of COX-2
Selenoproteins are essential molecules for the mammalian antioxidant network. We previously demonstrated that targeted loss of all selenoproteins in mouse epidermis disrupted skin and hair development and caused premature death. In the current study we targeted specific selenoproteins for epidermal...
Autores principales: | Sengupta, Aniruddha, Lichti, Ulrike F., Carlson, Bradley A., Cataisson, Christophe, Ryscavage, Andrew O., Mikulec, Carol, Conrad, Marcus, Fischer, Susan M., Hatfield, Dolph L., Yuspa, Stuart H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652900/ https://www.ncbi.nlm.nih.gov/pubmed/23364477 http://dx.doi.org/10.1038/jid.2013.52 |
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