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Differentiated Thyroid Carcinoma of Children and Adolescents: 27-Year Experience in the Yonsei University Health System
Thyroid carcinomas are uncommon in childhood and adolescence. The aim of this study was to analyze clinical features and clinical outcomes of thyroid cancer in the pediatric population treated in the Yonsei University Health System. From September 1982 to June 2009, 90 patients (75 females, 15 males...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Korean Academy of Medical Sciences
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653081/ https://www.ncbi.nlm.nih.gov/pubmed/23678260 http://dx.doi.org/10.3346/jkms.2013.28.5.693 |
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author | Park, Seulkee Jeong, Jun Soo Ryu, Haeng Rang Lee, Cho-Rok Park, Jae Hyun Kang, Sang-Wook Jeong, Jong Ju Nam, Kee-Hyun Chung, Woong Youn Park, Cheong Soo |
author_facet | Park, Seulkee Jeong, Jun Soo Ryu, Haeng Rang Lee, Cho-Rok Park, Jae Hyun Kang, Sang-Wook Jeong, Jong Ju Nam, Kee-Hyun Chung, Woong Youn Park, Cheong Soo |
author_sort | Park, Seulkee |
collection | PubMed |
description | Thyroid carcinomas are uncommon in childhood and adolescence. The aim of this study was to analyze clinical features and clinical outcomes of thyroid cancer in the pediatric population treated in the Yonsei University Health System. From September 1982 to June 2009, 90 patients (75 females, 15 males; female:male ratio of 5:1) with differentiated thyroid carcinoma were identified in our institute. The mean age at diagnosis was 15.8 yr old (range 4.8-19.9 yr). Cervical masses were most common clinical manifestations at diagnosis in 65 patients (72.2%). Forty-two patients underwent less than total thyroidectomy and 18 patients underwent total thyroidectomy. Thirty patients (33.3%) had lateral neck lymph node metastasis and seven patients (7.8%) had lung metastasis at the time of surgery. Among the 90 patients, recurrence occurred in 14 patients (15.5%). Mean follow-up period for patients with differentiated thyroid carcinoma was 81.6 months (13-324 months). No patients died of differentiated thyroid carcinoma. Patients with differentiated thyroid carcinoma who were < 20-yr-of-age were present with aggressive local disease and a high frequency of lymph node and distant metastasis. It is recommended that pediatric thyroid cancer should be managed mostly using proper surgical approach with thyroidectomy and lymph node dissection when indicated. |
format | Online Article Text |
id | pubmed-3653081 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | The Korean Academy of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-36530812013-05-15 Differentiated Thyroid Carcinoma of Children and Adolescents: 27-Year Experience in the Yonsei University Health System Park, Seulkee Jeong, Jun Soo Ryu, Haeng Rang Lee, Cho-Rok Park, Jae Hyun Kang, Sang-Wook Jeong, Jong Ju Nam, Kee-Hyun Chung, Woong Youn Park, Cheong Soo J Korean Med Sci Original Article Thyroid carcinomas are uncommon in childhood and adolescence. The aim of this study was to analyze clinical features and clinical outcomes of thyroid cancer in the pediatric population treated in the Yonsei University Health System. From September 1982 to June 2009, 90 patients (75 females, 15 males; female:male ratio of 5:1) with differentiated thyroid carcinoma were identified in our institute. The mean age at diagnosis was 15.8 yr old (range 4.8-19.9 yr). Cervical masses were most common clinical manifestations at diagnosis in 65 patients (72.2%). Forty-two patients underwent less than total thyroidectomy and 18 patients underwent total thyroidectomy. Thirty patients (33.3%) had lateral neck lymph node metastasis and seven patients (7.8%) had lung metastasis at the time of surgery. Among the 90 patients, recurrence occurred in 14 patients (15.5%). Mean follow-up period for patients with differentiated thyroid carcinoma was 81.6 months (13-324 months). No patients died of differentiated thyroid carcinoma. Patients with differentiated thyroid carcinoma who were < 20-yr-of-age were present with aggressive local disease and a high frequency of lymph node and distant metastasis. It is recommended that pediatric thyroid cancer should be managed mostly using proper surgical approach with thyroidectomy and lymph node dissection when indicated. The Korean Academy of Medical Sciences 2013-05 2013-05-02 /pmc/articles/PMC3653081/ /pubmed/23678260 http://dx.doi.org/10.3346/jkms.2013.28.5.693 Text en © 2013 The Korean Academy of Medical Sciences. http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Park, Seulkee Jeong, Jun Soo Ryu, Haeng Rang Lee, Cho-Rok Park, Jae Hyun Kang, Sang-Wook Jeong, Jong Ju Nam, Kee-Hyun Chung, Woong Youn Park, Cheong Soo Differentiated Thyroid Carcinoma of Children and Adolescents: 27-Year Experience in the Yonsei University Health System |
title | Differentiated Thyroid Carcinoma of Children and Adolescents: 27-Year Experience in the Yonsei University Health System |
title_full | Differentiated Thyroid Carcinoma of Children and Adolescents: 27-Year Experience in the Yonsei University Health System |
title_fullStr | Differentiated Thyroid Carcinoma of Children and Adolescents: 27-Year Experience in the Yonsei University Health System |
title_full_unstemmed | Differentiated Thyroid Carcinoma of Children and Adolescents: 27-Year Experience in the Yonsei University Health System |
title_short | Differentiated Thyroid Carcinoma of Children and Adolescents: 27-Year Experience in the Yonsei University Health System |
title_sort | differentiated thyroid carcinoma of children and adolescents: 27-year experience in the yonsei university health system |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653081/ https://www.ncbi.nlm.nih.gov/pubmed/23678260 http://dx.doi.org/10.3346/jkms.2013.28.5.693 |
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