A pilot study of the effect of spironolactone therapy on exercise capacity and endothelial dysfunction in pulmonary arterial hypertension: study protocol for a randomized controlled trial

BACKGROUND: Pulmonary arterial hypertension is a rare disorder associated with poor survival. Endothelial dysfunction plays a central role in the pathogenesis and progression of pulmonary arterial hypertension. Inflammation appears to drive this dysfunctional endothelial phenotype, propagating cycle...

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Detalles Bibliográficos
Autores principales: Elinoff, Jason M, Rame, J Eduardo, Forfia, Paul R, Hall, Mary K, Sun, Junfeng, Gharib, Ahmed M, Abd-Elmoniem, Khaled, Graninger, Grace, Harper, Bonnie, Danner, Robert L, Solomon, Michael A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653687/
https://www.ncbi.nlm.nih.gov/pubmed/23547564
http://dx.doi.org/10.1186/1745-6215-14-91

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