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Subhealth: definition, criteria for diagnosis and potential prevalence in the central region of China

BACKGROUND: A full evaluation of health conditions is necessary for the effective implementation of public health interventions. However, terms to address the intermediate state between health and disease are lacking, leading the public to overlook this state and thus increasing the risks of develop...

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Autores principales: Li, Guolin, Xie, Fuxia, Yan, Siyu, Hu, Xiaofei, Jin, Bo, Wang, Jun, Wu, Jinfeng, Yin, Dazhong, Xie, Qingji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653693/
https://www.ncbi.nlm.nih.gov/pubmed/23642312
http://dx.doi.org/10.1186/1471-2458-13-446
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author Li, Guolin
Xie, Fuxia
Yan, Siyu
Hu, Xiaofei
Jin, Bo
Wang, Jun
Wu, Jinfeng
Yin, Dazhong
Xie, Qingji
author_facet Li, Guolin
Xie, Fuxia
Yan, Siyu
Hu, Xiaofei
Jin, Bo
Wang, Jun
Wu, Jinfeng
Yin, Dazhong
Xie, Qingji
author_sort Li, Guolin
collection PubMed
description BACKGROUND: A full evaluation of health conditions is necessary for the effective implementation of public health interventions. However, terms to address the intermediate state between health and disease are lacking, leading the public to overlook this state and thus increasing the risks of developing disease. METHODS: A cross-sectional health survey of 1,473 randomly recruited Chinese Han adults of both sexes living in the central region of China. The criteria for diagnosis of subhealth was defined as the presence of ≥ 1 of the following abnormalities: body mass index ≥ 25 kg/m(2) or waist circumference ≥ 102 cm in men and 88 cm in women; systolic pressure 120–139 mmHg and/or diastolic pressure 80–89 mmHg; serum triglyceride level ≥ 150 mg/dL and/or total cholesterol level ≥ 200 mg/dL and/or high-density lipoprotein cholesterol level < 40 mg/dL in men and 50 mg/dL in women; serum glucose level 110–125 mg/dL; estimated glomerular filtration rate 60–89 ml/min/1.73 m(2); levels of liver enzymes in liver function tests between 41–59 U/L, or with fatty liver disease but < 33% of affected hepatocytes; levels of oxidative stress biomarkers beyond the reference range of 95%; or problems with both sleep quality and psychological state. RESULTS: The prevalences of subhealth and disease in the central region of China were 36.6% and 43.1%, respectively. The prevalence of disease increased from 26.3% in participants aged 20–39 years, to 47.6% and 78.9% for participants aged 40–59 years and those aged 60 years or older, respectively. Compared with participants aged 20–39, the prevalences of health and subhealth in participants aged 60 years or older decreased by 86.7% and 60.3%, respectively. The prevalence of subhealth was increased in association with increases in lifestyle risk scores, while the prevalences of both health and disease were reduced. CONCLUSION: The prevalences of subhealth and disease are high in central China. Subhealth is associated with high lifestyle risk scores. Both the health care sector and the public should pay more attention to subhealth. Lifestyle modifications and/or psychological interventions are needed to ameliorate these conditions.
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spelling pubmed-36536932013-05-15 Subhealth: definition, criteria for diagnosis and potential prevalence in the central region of China Li, Guolin Xie, Fuxia Yan, Siyu Hu, Xiaofei Jin, Bo Wang, Jun Wu, Jinfeng Yin, Dazhong Xie, Qingji BMC Public Health Research Article BACKGROUND: A full evaluation of health conditions is necessary for the effective implementation of public health interventions. However, terms to address the intermediate state between health and disease are lacking, leading the public to overlook this state and thus increasing the risks of developing disease. METHODS: A cross-sectional health survey of 1,473 randomly recruited Chinese Han adults of both sexes living in the central region of China. The criteria for diagnosis of subhealth was defined as the presence of ≥ 1 of the following abnormalities: body mass index ≥ 25 kg/m(2) or waist circumference ≥ 102 cm in men and 88 cm in women; systolic pressure 120–139 mmHg and/or diastolic pressure 80–89 mmHg; serum triglyceride level ≥ 150 mg/dL and/or total cholesterol level ≥ 200 mg/dL and/or high-density lipoprotein cholesterol level < 40 mg/dL in men and 50 mg/dL in women; serum glucose level 110–125 mg/dL; estimated glomerular filtration rate 60–89 ml/min/1.73 m(2); levels of liver enzymes in liver function tests between 41–59 U/L, or with fatty liver disease but < 33% of affected hepatocytes; levels of oxidative stress biomarkers beyond the reference range of 95%; or problems with both sleep quality and psychological state. RESULTS: The prevalences of subhealth and disease in the central region of China were 36.6% and 43.1%, respectively. The prevalence of disease increased from 26.3% in participants aged 20–39 years, to 47.6% and 78.9% for participants aged 40–59 years and those aged 60 years or older, respectively. Compared with participants aged 20–39, the prevalences of health and subhealth in participants aged 60 years or older decreased by 86.7% and 60.3%, respectively. The prevalence of subhealth was increased in association with increases in lifestyle risk scores, while the prevalences of both health and disease were reduced. CONCLUSION: The prevalences of subhealth and disease are high in central China. Subhealth is associated with high lifestyle risk scores. Both the health care sector and the public should pay more attention to subhealth. Lifestyle modifications and/or psychological interventions are needed to ameliorate these conditions. BioMed Central 2013-05-04 /pmc/articles/PMC3653693/ /pubmed/23642312 http://dx.doi.org/10.1186/1471-2458-13-446 Text en Copyright © 2013 Li et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Li, Guolin
Xie, Fuxia
Yan, Siyu
Hu, Xiaofei
Jin, Bo
Wang, Jun
Wu, Jinfeng
Yin, Dazhong
Xie, Qingji
Subhealth: definition, criteria for diagnosis and potential prevalence in the central region of China
title Subhealth: definition, criteria for diagnosis and potential prevalence in the central region of China
title_full Subhealth: definition, criteria for diagnosis and potential prevalence in the central region of China
title_fullStr Subhealth: definition, criteria for diagnosis and potential prevalence in the central region of China
title_full_unstemmed Subhealth: definition, criteria for diagnosis and potential prevalence in the central region of China
title_short Subhealth: definition, criteria for diagnosis and potential prevalence in the central region of China
title_sort subhealth: definition, criteria for diagnosis and potential prevalence in the central region of china
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653693/
https://www.ncbi.nlm.nih.gov/pubmed/23642312
http://dx.doi.org/10.1186/1471-2458-13-446
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