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5′-methylcytosine and 5′-hydroxymethylcytosine Each Provide Epigenetic Information to the Mouse Zygote
Covalent modification of cytosine nucleotides within the genome encode essential epigenetic information, with methylation (5meC) and hydroxymethylation (5hmC) having received most attention. It has been proposed that the formation of 5hmC is an intermediate in the active demethylation of 5meC. Some...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653832/ https://www.ncbi.nlm.nih.gov/pubmed/23691085 http://dx.doi.org/10.1371/journal.pone.0063689 |