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Selective Roles of Normal and Mutant Huntingtin in Neural Induction and Early Neurogenesis
Huntington's disease (HD) is a neurodegenerative disorder caused by abnormal polyglutamine expansion in the amino-terminal end of the huntingtin protein (Htt) and characterized by progressive striatal and cortical pathology. Previous reports have shown that Htt is essential for embryogenesis, a...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653864/ https://www.ncbi.nlm.nih.gov/pubmed/23691206 http://dx.doi.org/10.1371/journal.pone.0064368 |