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Top-Down Clustering for Protein Subfamily Identification

We propose a novel method for the task of protein subfamily identification; that is, finding subgroups of functionally closely related sequences within a protein family. In line with phylogenomic analysis, the method first builds a hierarchical tree using as input a multiple alignment of the protein...

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Detalles Bibliográficos
Autores principales: Costa, Eduardo P., Vens, Celine, Blockeel, Hendrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653887/
https://www.ncbi.nlm.nih.gov/pubmed/23700359
http://dx.doi.org/10.4137/EBO.S11609