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Phenotypical Analysis of Atypical PKCs In Vivo Function Display a Compensatory System at Mouse Embryonic Day 7.5
BACKGROUND: The atypical protein kinases C (PKC) isoforms ι/λ and ζ play crucial roles in many cellular processes including development, cell proliferation, differentiation and cell survival. Possible redundancy between the two isoforms has always been an issue since most biochemical tools do not di...
Autores principales: | Seidl, Sebastian, Braun, Ursula, Roos, Norbert, Li, Shaohua, Lüdtke, Timo H.-W., Kispert, Andreas, Leitges, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653893/ https://www.ncbi.nlm.nih.gov/pubmed/23690951 http://dx.doi.org/10.1371/journal.pone.0062756 |
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