Analysis of Tumor Heterogeneity and Cancer Gene Networks Using Deep Sequencing of MMTV-Induced Mouse Mammary Tumors

Cancer develops through a multistep process in which normal cells progress to malignant tumors via the evolution of their genomes as a result of the acquisition of mutations in cancer driver genes. The number, identity and mode of action of cancer driver genes, and how they contribute to tumor evolu...

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Detalles Bibliográficos
Autores principales: Klijn, Christiaan, Koudijs, Marco J., Kool, Jaap, ten Hoeve, Jelle, Boer, Mandy, de Moes, Joost, Akhtar, Waseem, van Miltenburg, Martine, Vendel-Zwaagstra, Annabel, Reinders, Marcel J. T., Adams, David J., van Lohuizen, Maarten, Hilkens, John, Wessels, Lodewyk F. A., Jonkers, Jos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653918/
https://www.ncbi.nlm.nih.gov/pubmed/23690930
http://dx.doi.org/10.1371/journal.pone.0062113

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