TLR4 Activates the β-catenin Pathway to Cause Intestinal Neoplasia

Colonic bacteria have been implicated in the development of colon cancer. We have previously demonstrated that toll-like receptor 4 (TLR4), the receptor for bacterial lipopolysaccharide (LPS), is over-expressed in humans with colitis-associated cancer. Genetic epidemiologic data support a role for T...

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Detalles Bibliográficos
Autores principales: Santaolalla, Rebeca, Sussman, Daniel A., Ruiz, Jose R., Davies, Julie M., Pastorini, Cristhine, España, Cecilia L., Sotolongo, John, Burlingame, Oname, Bejarano, Pablo A., Philip, Sakhi, Ahmed, Mansoor M., Ko, Jeffrey, Dirisina, Ramanarao, Barrett, Terrence A., Shang, Limin, Lira, Sergio A., Fukata, Masayuki, Abreu, Maria T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653932/
https://www.ncbi.nlm.nih.gov/pubmed/23691015
http://dx.doi.org/10.1371/journal.pone.0063298

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