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β-Catenin Functions Pleiotropically in Differentiation and Tumorigenesis in Mouse Embryo-Derived Stem Cells

The canonical Wnt/β-catenin signaling pathway plays a crucial role in the maintenance of the balance between proliferation and differentiation throughout embryogenesis and tissue homeostasis. β-Catenin, encoded by the Ctnnb1 gene, mediates an intracellular signaling cascade activated by Wnt. It also...

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Detalles Bibliográficos
Autores principales:	Okumura, Noriko, Akutsu, Hidenori, Sugawara, Tohru, Miura, Takumi, Takezawa, Youki, Hosoda, Akihiro, Yoshida, Keiichi, Ichida, Justin K., Yamada, Mitsutoshi, Hamatani, Toshio, Kuji, Naoaki, Miyado, Kenji, Yoshimura, Yasunori, Umezawa, Akihiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653942/ https://www.ncbi.nlm.nih.gov/pubmed/23691006 http://dx.doi.org/10.1371/journal.pone.0063265

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