IKBKE Phosphorylation and Inhibition of FOXO3a: A Mechanism of IKBKE Oncogenic Function

Forkhead box O (FOXO) transcription factors are emerging as key regulators of cell survival and growth. The transcriptional activity and subcellular localization of FOXO are tightly regulated by post-translational modifications. Here we report that IKBKE regulates FOXO3a through phosphorylation of F...

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Detalles Bibliográficos
Autores principales: Guo, Jian-Ping, Tian, Wei, Shu, Shaokun, Xin, Yu, Shou, Chengchao, Cheng, Jin Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653944/
https://www.ncbi.nlm.nih.gov/pubmed/23691078
http://dx.doi.org/10.1371/journal.pone.0063636

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653944/
https://www.ncbi.nlm.nih.gov/pubmed/23691078
http://dx.doi.org/10.1371/journal.pone.0063636

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