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TREX exposes the RNA binding domain of Nxf1 to enable mRNA export

The metazoan TREX complex is recruited to mRNA during nuclear RNA processing and functions in exporting mRNA to the cytoplasm. Nxf1 is an mRNA export receptor, which binds processed mRNA and transports it through the nuclear pore complex. At present, the relationship between TREX and Nxf1 is not und...

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Detalles Bibliográficos
Autores principales: Viphakone, Nicolas, Hautbergue, Guillaume M., Walsh, Matthew, Chang, Chung-Te, Holland, Arthur, Folco, Eric G., Reed, Robin, Wilson, Stuart A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654228/
https://www.ncbi.nlm.nih.gov/pubmed/22893130
http://dx.doi.org/10.1038/ncomms2005