Hepatitis C Virus Infection: Looking for Interferon Free Regimens

Recent developments of new drugs' combinations are changing the treatment paradigm in hepatitis C virus infection. Due to the side effect profile of pegylated interferons, interferon-sparing regimens have become the main target in chronic hepatitis C treatment research. Recent proofs of concept...

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Detalles Bibliográficos
Autores principales: González-Moreno, J., Payeras-Cifre, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654259/
https://www.ncbi.nlm.nih.gov/pubmed/23710151
http://dx.doi.org/10.1155/2013/825375
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author González-Moreno, J.
Payeras-Cifre, A.
author_facet González-Moreno, J.
Payeras-Cifre, A.
author_sort González-Moreno, J.
collection PubMed
description Recent developments of new drugs' combinations are changing the treatment paradigm in hepatitis C virus infection. Due to the side effect profile of pegylated interferons, interferon-sparing regimens have become the main target in chronic hepatitis C treatment research. Recent proofs of concept studies have suggested that cure of chronic hepatitis C can be achieved without interferon. The purpose of this paper is to provide an overview of the clinical results recently reported for the treatment of hepatitis C virus infection with interferon-free regimens, focusing on the most promising new compounds and combinations.
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spelling pubmed-36542592013-05-24 Hepatitis C Virus Infection: Looking for Interferon Free Regimens González-Moreno, J. Payeras-Cifre, A. ScientificWorldJournal Review Article Recent developments of new drugs' combinations are changing the treatment paradigm in hepatitis C virus infection. Due to the side effect profile of pegylated interferons, interferon-sparing regimens have become the main target in chronic hepatitis C treatment research. Recent proofs of concept studies have suggested that cure of chronic hepatitis C can be achieved without interferon. The purpose of this paper is to provide an overview of the clinical results recently reported for the treatment of hepatitis C virus infection with interferon-free regimens, focusing on the most promising new compounds and combinations. Hindawi Publishing Corporation 2013-04-09 /pmc/articles/PMC3654259/ /pubmed/23710151 http://dx.doi.org/10.1155/2013/825375 Text en Copyright © 2013 J. González-Moreno and A. Payeras-Cifre. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
González-Moreno, J.
Payeras-Cifre, A.
Hepatitis C Virus Infection: Looking for Interferon Free Regimens
title Hepatitis C Virus Infection: Looking for Interferon Free Regimens
title_full Hepatitis C Virus Infection: Looking for Interferon Free Regimens
title_fullStr Hepatitis C Virus Infection: Looking for Interferon Free Regimens
title_full_unstemmed Hepatitis C Virus Infection: Looking for Interferon Free Regimens
title_short Hepatitis C Virus Infection: Looking for Interferon Free Regimens
title_sort hepatitis c virus infection: looking for interferon free regimens
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654259/
https://www.ncbi.nlm.nih.gov/pubmed/23710151
http://dx.doi.org/10.1155/2013/825375
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