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BUBR1 recruits PP2A via the B56 family of targeting subunits to promote chromosome congression

BUBR1 is a mitotic phosphoprotein essential for the maintenance of chromosome stability by promoting chromosome congression and proper kinetochore–microtubule (K-fiber) attachment, but the underlying mechanism(s) has remained elusive. Here we identify BUBR1 as a binding partner of the B56 family of...

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Detalles Bibliográficos
Autores principales: Xu, Peng, Raetz, Elizabeth A., Kitagawa, Mayumi, Virshup, David M., Lee, Sang Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654266/
https://www.ncbi.nlm.nih.gov/pubmed/23789096
http://dx.doi.org/10.1242/bio.20134051

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