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Modulatory effect of BclI GR gene polymorphisms on the obesity phenotype in Brazilian patients with Cushing's disease

OBJECTIVES: Patients with Cushing's disease exhibit wide phenotypic variability in the severity of obesity, diabetes and hypertension. In the general population, several glucocorticoid receptor genes (NR3C1) and HSD11B1 polymorphisms are associated with altered glucocorticoid sensitivity and/or...

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Detalles Bibliográficos
Autores principales:	Moreira, Ricardo P. P., Bachega, Tânia A. S. S., Machado, Márcio C., Mendonca, Berenice B., Bronstein, Marcello D., Villares Fragoso, Maria Candida B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2013
Materias:	Clinical Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654304/ https://www.ncbi.nlm.nih.gov/pubmed/23778418 http://dx.doi.org/10.6061/clinics/2013(05)01

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