Cargando…

NRF2-ome: An Integrated Web Resource to Discover Protein Interaction and Regulatory Networks of NRF2

NRF2 is the master transcriptional regulator of oxidative and xenobiotic stress responses. NRF2 has important roles in carcinogenesis, inflammation, and neurodegenerative diseases. We developed an online resource, NRF2-ome, to provide an integrated and systems-level database for NRF2. The database c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Türei, Dénes, Papp, Diána, Fazekas, Dávid, Földvári-Nagy, László, Módos, Dezső, Lenti, Katalin, Csermely, Péter, Korcsmáros, Tamás
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654349/ https://www.ncbi.nlm.nih.gov/pubmed/23710289 http://dx.doi.org/10.1155/2013/737591

Ejemplares similares

Autophagy Regulatory Network — A systems-level bioinformatics resource for studying the mechanism and regulation of autophagy
por: Türei, Dénes, et al.
Publicado: (2015)

Targets of drugs are generally, and targets of drugs having side effects are specifically good spreaders of human interactome perturbations
por: Perez-Lopez, Áron R., et al.
Publicado: (2015)

SignaLink 2 – a signaling pathway resource with multi-layered regulatory networks
por: Fazekas, Dávid, et al.
Publicado: (2013)

Identification of critical paralog groups with indispensable roles in the regulation of signaling flow
por: Modos, Dezso, et al.
Publicado: (2016)

SignaLink3: a multi-layered resource to uncover tissue-specific signaling networks
por: Csabai, Luca, et al.
Publicado: (2021)

On the role of bacterial metalloproteases in COVID-19 associated cytokine storm
por: Földvári-Nagy, László, et al.
Publicado: (2021)

Starvation-response may not involve Atg1-dependent autophagy induction in non-unikont parasites
por: Földvári-Nagy, László, et al.
Publicado: (2014)

Neighbours of cancer-related proteins have key influence on pathogenesis and could increase the drug target space for anticancer therapies
por: Módos, Dezső, et al.
Publicado: (2017)

Systems-Level Feedbacks of NRF2 Controlling Autophagy upon Oxidative Stress Response
por: Kapuy, Orsolya, et al.
Publicado: (2018)

A Role for SKN-1/Nrf in Pathogen Resistance and Immunosenescence in Caenorhabditis elegans
por: Papp, Diána, et al.
Publicado: (2012)

Signalogs: Orthology-Based Identification of Novel Signaling Pathway Components in Three Metazoans
por: Korcsmáros, Tamás, et al.
Publicado: (2011)

Integrated intra‐ and intercellular signaling knowledge for multicellular omics analysis
por: Türei, Dénes, et al.
Publicado: (2021)

Suppression of AMPK/aak-2 by NRF2/SKN-1 down-regulates autophagy during prolonged oxidative stress
por: Kosztelnik, Monika, et al.
Publicado: (2019)

Network Biology Approaches to Achieve Precision Medicine in Inflammatory Bowel Disease
por: Thomas, John P, et al.
Publicado: (2021)

The Emerging Role of Bile Acids in the Pathogenesis of Inflammatory Bowel Disease
por: Thomas, John P., et al.
Publicado: (2022)

Analysing miRNA-Target Gene Networks in Inflammatory Bowel Disease and Other Complex Diseases Using Transcriptomic Data
por: Thomas, John P., et al.
Publicado: (2022)

Mapping the epithelial–immune cell interactome upon infection in the gut and the upper airways
por: Poletti, Martina, et al.
Publicado: (2022)

Nrf2 and the Nrf2-Interacting Network in Respiratory Inflammation and Diseases
por: Carlson, Jennifer, et al.
Publicado: (2020)

The NRF2-p97-NRF2 negative feedback loop
por: Shakya, Aryatara, et al.
Publicado: (2023)

Bcl-2-Ome – a database and interactive web service for dissecting the Bcl-2 interactome
por: Hantusch, Annika, et al.
Publicado: (2017)

ComPPI: a cellular compartment-specific database for protein–protein interaction network analysis
por: Veres, Daniel V., et al.
Publicado: (2015)

SARS-CoV-2 Causes a Different Cytokine Response Compared to Other Cytokine Storm-Causing Respiratory Viruses in Severely Ill Patients
por: Olbei, Marton, et al.
Publicado: (2021)

COPD lung studies of Nrf2 expression and the effects of Nrf2 activators
por: Li, Jian, et al.
Publicado: (2022)

Defining the Functional Targets of Cap‘n’collar Transcription Factors NRF1, NRF2, and NRF3
por: Ibrahim, Lara, et al.
Publicado: (2020)

Roles of CNC Transcription Factors NRF1 and NRF2 in Cancer
por: Sekine, Hiroki, et al.
Publicado: (2021)

Polymorphisms of NRF2 and NRF2 target genes in urinary bladder cancer patients
por: Reszka, Edyta, et al.
Publicado: (2014)

How to deal with frenemy NRF2: Targeting NRF2 for chemoprevention and cancer therapy
por: Tang, Ya-Chu, et al.
Publicado: (2023)

Nrf2 and Cardiovascular Defense
por: Howden, Reuben
Publicado: (2013)

NRF2 molecule of the month
por: Shapshak, Paul
Publicado: (2012)

Nrf2: not “lost in translation”
por: Hawley, Robert G., et al.
Publicado: (2016)

Transcriptional Regulation by Nrf2
por: Tonelli, Claudia, et al.
Publicado: (2018)

Nrf2, stress and aging
por: Trougakos, Ioannis P.
Publicado: (2019)

NRF2 in Viral Infection
por: Herengt, Angela, et al.
Publicado: (2021)

Macrophage Nrf 2 the rescue
por: Stow, Jennifer L., et al.
Publicado: (2023)

No place like Ome
por: Petsko, Gregory A
Publicado: (2002)

Reading and writing omes
por: Church, George M
Publicado: (2013)

HDL functionality is dependent on hepatocyte stress defense factors Nrf1 and Nrf2
por: Trites, Michael J., et al.
Publicado: (2023)

Antioxidant Effects of Statins by Modulating Nrf2 and Nrf2/HO-1 Signaling in Different Diseases
por: Mansouri, Atena, et al.
Publicado: (2022)

Hypermethylation of the Nrf2 Promoter Induces Ferroptosis by Inhibiting the Nrf2-GPX4 Axis in COPD
por: Zhang, Zixiao, et al.
Publicado: (2021)

Phytochemical activators of Nrf2: a review of therapeutic strategies in diabetes: Phytochemical activators of Nrf2
por: Qin, Si, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_9a8ai7v9jj6cfur6bc5u0om1pa