Targeting cathepsin G in myeloid leukemia

Cathepsin G (CG) is a serine protease normally found within the azurophil granules of neutrophils. CG is expressed during the early stages of normal myeloid differentiation and—aberrantly—by myeloid leukemia cells. We have recently identified CG-derived HLA-A*0201-binding peptides that constitute pr...

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Detalles Bibliográficos
Autor principal: Alatrash, Gheath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654578/
https://www.ncbi.nlm.nih.gov/pubmed/23734308
http://dx.doi.org/10.4161/onci.23442
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author Alatrash, Gheath
author_facet Alatrash, Gheath
author_sort Alatrash, Gheath
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description Cathepsin G (CG) is a serine protease normally found within the azurophil granules of neutrophils. CG is expressed during the early stages of normal myeloid differentiation and—aberrantly—by myeloid leukemia cells. We have recently identified CG-derived HLA-A*0201-binding peptides that constitute promising targets for the immunotherapy of myeloid leukemia.
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spelling pubmed-36545782013-06-03 Targeting cathepsin G in myeloid leukemia Alatrash, Gheath Oncoimmunology Author's View Cathepsin G (CG) is a serine protease normally found within the azurophil granules of neutrophils. CG is expressed during the early stages of normal myeloid differentiation and—aberrantly—by myeloid leukemia cells. We have recently identified CG-derived HLA-A*0201-binding peptides that constitute promising targets for the immunotherapy of myeloid leukemia. Landes Bioscience 2013-04-01 2013-04-01 /pmc/articles/PMC3654578/ /pubmed/23734308 http://dx.doi.org/10.4161/onci.23442 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Alatrash, Gheath
Targeting cathepsin G in myeloid leukemia
title Targeting cathepsin G in myeloid leukemia
title_full Targeting cathepsin G in myeloid leukemia
title_fullStr Targeting cathepsin G in myeloid leukemia
title_full_unstemmed Targeting cathepsin G in myeloid leukemia
title_short Targeting cathepsin G in myeloid leukemia
title_sort targeting cathepsin g in myeloid leukemia
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654578/
https://www.ncbi.nlm.nih.gov/pubmed/23734308
http://dx.doi.org/10.4161/onci.23442
work_keys_str_mv AT alatrashgheath targetingcathepsinginmyeloidleukemia

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