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Targeting cathepsin G in myeloid leukemia
Cathepsin G (CG) is a serine protease normally found within the azurophil granules of neutrophils. CG is expressed during the early stages of normal myeloid differentiation and—aberrantly—by myeloid leukemia cells. We have recently identified CG-derived HLA-A*0201-binding peptides that constitute pr...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Landes Bioscience
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654578/ https://www.ncbi.nlm.nih.gov/pubmed/23734308 http://dx.doi.org/10.4161/onci.23442 |