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Immunomodulation of the tumor microenvironment by Toll-like receptor-3 (TLR3) ligands
In hepatocellular carcinoma (HCC) patients, the intratumoral expression of Toll-like receptor-3 (TLR3) correlates with prolonged survival. We demonstrated that TLR3 ligands can operate through three independent mechanisms: by directly killing TLR3-expressing cancer cells, by inducing T- and natural...
Autores principales: | Chew, Valerie, Abastado, Jean-Pierre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654580/ https://www.ncbi.nlm.nih.gov/pubmed/23734310 http://dx.doi.org/10.4161/onci.23493 |
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