The RIG-I/MAVS signaling pathway in cancer cell-selective apoptosis

A replication-incompetent hemagglutinating virus of Japan (HVJ) envelope (HVJ-E) induces apoptosis selectively in cancer cells. Fragments of the viral RNA genome transported by HVJ-E are recognized by retinoic acid-inducible gene I (RIG-I) and mitochondrial antiviral signaling (MAVS). Specific pro-a...

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Detalles Bibliográficos
Autor principal: Kaneda, Yasufumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654583/
https://www.ncbi.nlm.nih.gov/pubmed/23734313
http://dx.doi.org/10.4161/onci.23566
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author Kaneda, Yasufumi
author_facet Kaneda, Yasufumi
author_sort Kaneda, Yasufumi
collection PubMed
description A replication-incompetent hemagglutinating virus of Japan (HVJ) envelope (HVJ-E) induces apoptosis selectively in cancer cells. Fragments of the viral RNA genome transported by HVJ-E are recognized by retinoic acid-inducible gene I (RIG-I) and mitochondrial antiviral signaling (MAVS). Specific pro-apoptotic factor are selectively upregulated in cancer cells downstream of the RIG-I/MAVS pathway.
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spelling pubmed-36545832013-06-03 The RIG-I/MAVS signaling pathway in cancer cell-selective apoptosis Kaneda, Yasufumi Oncoimmunology Author's View A replication-incompetent hemagglutinating virus of Japan (HVJ) envelope (HVJ-E) induces apoptosis selectively in cancer cells. Fragments of the viral RNA genome transported by HVJ-E are recognized by retinoic acid-inducible gene I (RIG-I) and mitochondrial antiviral signaling (MAVS). Specific pro-apoptotic factor are selectively upregulated in cancer cells downstream of the RIG-I/MAVS pathway. Landes Bioscience 2013-04-01 2013-04-01 /pmc/articles/PMC3654583/ /pubmed/23734313 http://dx.doi.org/10.4161/onci.23566 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Kaneda, Yasufumi
The RIG-I/MAVS signaling pathway in cancer cell-selective apoptosis
title The RIG-I/MAVS signaling pathway in cancer cell-selective apoptosis
title_full The RIG-I/MAVS signaling pathway in cancer cell-selective apoptosis
title_fullStr The RIG-I/MAVS signaling pathway in cancer cell-selective apoptosis
title_full_unstemmed The RIG-I/MAVS signaling pathway in cancer cell-selective apoptosis
title_short The RIG-I/MAVS signaling pathway in cancer cell-selective apoptosis
title_sort rig-i/mavs signaling pathway in cancer cell-selective apoptosis
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654583/
https://www.ncbi.nlm.nih.gov/pubmed/23734313
http://dx.doi.org/10.4161/onci.23566
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