Toll-like receptor 5 and the emerging role of bacteria in carcinogenesis

Toll-like receptor 5 (TLR5) is an pattern recognition receptor expressed by several cells of the immune system that recognizes bacterial flagellin. We studied the influence of TLR5 in oral tongue squamous carcinoma and found that its expression levels predict patient survival and recurrence. Conside...

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Autores principales: Kauppila, Joonas H., Mattila, Antti E., Karttunen, Tuomo J., Salo, Tuula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654585/
https://www.ncbi.nlm.nih.gov/pubmed/23734315
http://dx.doi.org/10.4161/onci.23620
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author Kauppila, Joonas H.
Mattila, Antti E.
Karttunen, Tuomo J.
Salo, Tuula
author_facet Kauppila, Joonas H.
Mattila, Antti E.
Karttunen, Tuomo J.
Salo, Tuula
author_sort Kauppila, Joonas H.
collection PubMed
description Toll-like receptor 5 (TLR5) is an pattern recognition receptor expressed by several cells of the immune system that recognizes bacterial flagellin. We studied the influence of TLR5 in oral tongue squamous carcinoma and found that its expression levels predict patient survival and recurrence. Considering the role of microbiome in oral cancer, TLR5 may represent an important link between bacteria and oral oncogenesis.
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spelling pubmed-36545852013-06-03 Toll-like receptor 5 and the emerging role of bacteria in carcinogenesis Kauppila, Joonas H. Mattila, Antti E. Karttunen, Tuomo J. Salo, Tuula Oncoimmunology Author's View Toll-like receptor 5 (TLR5) is an pattern recognition receptor expressed by several cells of the immune system that recognizes bacterial flagellin. We studied the influence of TLR5 in oral tongue squamous carcinoma and found that its expression levels predict patient survival and recurrence. Considering the role of microbiome in oral cancer, TLR5 may represent an important link between bacteria and oral oncogenesis. Landes Bioscience 2013-04-01 2013-04-01 /pmc/articles/PMC3654585/ /pubmed/23734315 http://dx.doi.org/10.4161/onci.23620 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Kauppila, Joonas H.
Mattila, Antti E.
Karttunen, Tuomo J.
Salo, Tuula
Toll-like receptor 5 and the emerging role of bacteria in carcinogenesis
title Toll-like receptor 5 and the emerging role of bacteria in carcinogenesis
title_full Toll-like receptor 5 and the emerging role of bacteria in carcinogenesis
title_fullStr Toll-like receptor 5 and the emerging role of bacteria in carcinogenesis
title_full_unstemmed Toll-like receptor 5 and the emerging role of bacteria in carcinogenesis
title_short Toll-like receptor 5 and the emerging role of bacteria in carcinogenesis
title_sort toll-like receptor 5 and the emerging role of bacteria in carcinogenesis
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654585/
https://www.ncbi.nlm.nih.gov/pubmed/23734315
http://dx.doi.org/10.4161/onci.23620
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