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A novel bispecific antibody recruits T cells to eradicate tumors in the “immunologically privileged” central nervous system
Bispecific T-cell engagers (BiTEs) may break multiple barriers that currently limit the use of immunotherapy in glioblastoma patients. We have recently described a novel BiTE specific for a mutated form of the epidermal growth factor receptor, EGFRvIII, that exerts potent antineoplastic effects agai...
Autores principales: | Choi, Bryan D., Pastan, Ira, Bigner, Darell D., Sampson, John H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654588/ https://www.ncbi.nlm.nih.gov/pubmed/23734318 http://dx.doi.org/10.4161/onci.23639 |
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