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The CCL5/CCR5 axis promotes metastasis in basal breast cancer

Recently, we have shown that the CCL5/CCR5 axis is active in patients affected by an aggressive basal subtype of breast cancer. Using preclinical models, we have demonstrated that CCR5 promotes breast cancer invasiveness and metastatic potential, while CCR5 inhibition abrogates them. Thus, CCR5 anta...

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Detalles Bibliográficos
Autores principales: Velasco-Velázquez, Marco, Pestell, Richard G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654591/
https://www.ncbi.nlm.nih.gov/pubmed/23734321
http://dx.doi.org/10.4161/onci.23660