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New antibiotic agents in the pipeline and how they can help overcome microbial resistance

Bacterial resistance is a growing threat and yet few new antibiotics active against multi-resistant bacteria are being explored. A combination of falling profits, regulatory mechanisms and irrational and injudicious use of antibiotics has led to an alarming situation where some infections have no cu...

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Detalles Bibliográficos
Autores principales: Gould, Ian M., Bal, Abhijit M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654619/
https://www.ncbi.nlm.nih.gov/pubmed/23302792
http://dx.doi.org/10.4161/viru.22507
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author Gould, Ian M.
Bal, Abhijit M.
author_facet Gould, Ian M.
Bal, Abhijit M.
author_sort Gould, Ian M.
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description Bacterial resistance is a growing threat and yet few new antibiotics active against multi-resistant bacteria are being explored. A combination of falling profits, regulatory mechanisms and irrational and injudicious use of antibiotics has led to an alarming situation where some infections have no cure. In this article, we summarize the new developments that have been suggested to incentivize the pharmaceutical industries toward the field of infections. We also briefly mention the new compounds on the horizon and some newly approved compounds that might help us tide over this crisis.
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spelling pubmed-36546192013-06-03 New antibiotic agents in the pipeline and how they can help overcome microbial resistance Gould, Ian M. Bal, Abhijit M. Virulence Review Bacterial resistance is a growing threat and yet few new antibiotics active against multi-resistant bacteria are being explored. A combination of falling profits, regulatory mechanisms and irrational and injudicious use of antibiotics has led to an alarming situation where some infections have no cure. In this article, we summarize the new developments that have been suggested to incentivize the pharmaceutical industries toward the field of infections. We also briefly mention the new compounds on the horizon and some newly approved compounds that might help us tide over this crisis. Landes Bioscience 2013-02-15 2013-01-09 /pmc/articles/PMC3654619/ /pubmed/23302792 http://dx.doi.org/10.4161/viru.22507 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Review
Gould, Ian M.
Bal, Abhijit M.
New antibiotic agents in the pipeline and how they can help overcome microbial resistance
title New antibiotic agents in the pipeline and how they can help overcome microbial resistance
title_full New antibiotic agents in the pipeline and how they can help overcome microbial resistance
title_fullStr New antibiotic agents in the pipeline and how they can help overcome microbial resistance
title_full_unstemmed New antibiotic agents in the pipeline and how they can help overcome microbial resistance
title_short New antibiotic agents in the pipeline and how they can help overcome microbial resistance
title_sort new antibiotic agents in the pipeline and how they can help overcome microbial resistance
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654619/
https://www.ncbi.nlm.nih.gov/pubmed/23302792
http://dx.doi.org/10.4161/viru.22507
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