Cargando…

Gene Therapy of Multiple Sclerosis Using Interferon β-Secreting Human Bone Marrow Mesenchymal Stem Cells

Interferon-beta (IFN-β), a well-established standard treatment for multiple sclerosis (MS), has proved to exhibit clinical efficacy. In this study, we first evaluated the therapeutic effects for MS using human bone marrow-derived mesenchymal stem cells (hBM-MSCs) as delivery vehicles with lesion-tar...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ryu, Chung Heon, Park, Kwang Ywel, Hou, Yun, Jeong, Chang Hyun, Kim, Seong Muk, Jeun, Sin-Soo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654641/ https://www.ncbi.nlm.nih.gov/pubmed/23710456 http://dx.doi.org/10.1155/2013/696738

Ejemplares similares

Effective combination of human bone marrow mesenchymal stem cells and minocycline in experimental autoimmune encephalomyelitis mice
por: Hou, Yun, et al.
Publicado: (2013)

Combination Therapy for Gliomas Using Temozolomide and Interferon-Beta Secreting Human Bone Marrow Derived Mesenchymal Stem Cells
por: Park, Jae-Hyun, et al.
Publicado: (2015)

Valproic Acid Downregulates the Expression of MGMT and Sensitizes Temozolomide-Resistant Glioma Cells
por: Ryu, Chung Heon, et al.
Publicado: (2012)

In vivo near-infrared imaging for the tracking of systemically delivered mesenchymal stem cells: tropism for brain tumors and biodistribution
por: Kim, Seong Muk, et al.
Publicado: (2015)

Mesenchymal Stem Cells Expressing Brain-Derived Neurotrophic Factor Enhance Endogenous Neurogenesis in an Ischemic Stroke Model
por: Jeong, Chang Hyun, et al.
Publicado: (2014)

Therapeutic effects of human umbilical cord blood-derived mesenchymal stem cells after intrathecal administration by lumbar puncture in a rat model of cerebral ischemia
por: Lim, Jung Yeon, et al.
Publicado: (2011)

Combination therapy of human bone marrow–derived mesenchymal stem cells and minocycline improves neuronal function in a rat middle cerebral artery occlusion model
por: Cho, Dong Young, et al.
Publicado: (2018)

Human Umbilical Cord Blood-Derived Mesenchymal Stem Cell Therapy Promotes Functional Recovery of Contused Rat Spinal Cord through Enhancement of Endogenous Cell Proliferation and Oligogenesis
por: Park, Sang In, et al.
Publicado: (2012)

Microporation is a valuable transfection method for efficient gene delivery into human umbilical cord blood-derived mesenchymal stem cells
por: Lim, Jung Yeon, et al.
Publicado: (2010)

Bone marrow sarcoidosis associated with long‐term interferon‐β treatment for multiple sclerosis
por: Teh, Angela, et al.
Publicado: (2016)

Combination treatment with VPA and MSCs-TRAIL could increase anti-tumor effects against intracranial glioma
por: Park, Soon A., et al.
Publicado: (2021)

GDNF secreted by pre-osteoclasts induces migration of bone marrow mesenchymal stem cells and stimulates osteogenesis
por: Yi, Sol, et al.
Publicado: (2020)

Interferon-Gamma Impairs Maintenance and Alters Hematopoietic Support of Bone Marrow Mesenchymal Stromal Cells
por: Goedhart, Marieke, et al.
Publicado: (2018)

Interferon γ induced compositional changes in human bone marrow derived mesenchymal stem/stromal cells
por: Guan, Qingdong, et al.
Publicado: (2017)

Neuron-Like Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells
por: Bae, Keum Seok, et al.
Publicado: (2011)

Secreted Frizzled-Related Protein Promotes Bone Regeneration by Human Bone Marrow-Derived Mesenchymal Stem Cells
por: Katagiri, Wataru, et al.
Publicado: (2015)

Bone Marrow Mesenchymal Stem Cells Inhibit the Function of Dendritic Cells by Secreting Galectin-1
por: Zhang, Yue, et al.
Publicado: (2017)

Secretion of interleukin-6 by bone marrow mesenchymal stem cells promotes metastasis in hepatocellular carcinoma
por: Mi, Fei, et al.
Publicado: (2017)

Repeat Administration of Bone Marrow-Derived Mesenchymal Stem Cells for Treatment of Amyotrophic Lateral Sclerosis
por: Siwek, Tomasz, et al.
Publicado: (2020)

Extra-Axial Medulloblastoma in the Cerebellar Hemisphere
por: Chung, Eui Jin, et al.
Publicado: (2014)

Bone marrow‐derived mesenchymal stem cells promote Helicobacter pylori‐associated gastric cancer progression by secreting thrombospondin‐2
por: Shi, Huiying, et al.
Publicado: (2021)

Bone Marrow-derived Mesenchymal Stem Cells Affect Immunologic Profiling of Interleukin-17-secreting Cells in a Chemical Burn Mouse Model
por: Lee, Ja Young, et al.
Publicado: (2014)

Safety and efficacy of bone marrow derived-mesenchymal stem cells transplantation in patients with amyotrophic lateral sclerosis
por: Tavakol-Afshari, Jalil, et al.
Publicado: (2021)

Protein synthesis and secretion in human mesenchymal cells derived from bone marrow, adipose tissue and Wharton’s jelly
por: Amable, Paola Romina, et al.
Publicado: (2014)

A comparison of adipose and bone marrow-derived mesenchymal stromal cell secreted factors in the treatment of systemic inflammation
por: Elman, Jessica S, et al.
Publicado: (2014)

Bone marrow-derived mesenchymal stem cell-secreted IL-8 promotes the angiogenesis and growth of colorectal cancer
por: Wang, Jiancheng, et al.
Publicado: (2015)

Population doubling level-dependent change of secreted glycosaminoglycan in equine bone marrow-derived mesenchymal stem cells
por: SASAO, Takafumi, et al.
Publicado: (2015)

Gametocytes of the Malaria Parasite Plasmodium falciparum Interact With and Stimulate Bone Marrow Mesenchymal Cells to Secrete Angiogenetic Factors
por: Messina, Valeria, et al.
Publicado: (2018)

A Novel Immunomodulatory Mechanism Dependent on Acetylcholine Secreted by Human Bone Marrow-derived Mesenchymal Stem Cells
por: Yi, Tac-Ghee, et al.
Publicado: (2019)

Ibuprofen in Therapeutic Concentrations Affects the Secretion of Human Bone Marrow Mesenchymal Stromal Cells, but Not Their Proliferative and Migratory Capacity
por: Kulesza, Agnieszka, et al.
Publicado: (2022)

CYTL1 regulates bone homeostasis in mice by modulating osteogenesis of mesenchymal stem cells and osteoclastogenesis of bone marrow-derived macrophages
por: Shin, Youngnim, et al.
Publicado: (2019)

Bone marrow mesenchymal stem cells as a possible ruxolitinib reservoir in the bone marrow niche
por: Marino, Luigi, et al.
Publicado: (2020)

Enzyme‐Cleaved Bone Marrow Transplantation Improves the Engraftment of Bone Marrow Mesenchymal Stem Cells
por: Kawai, Hotaka, et al.
Publicado: (2023)

Effect of Multiple Intraperitoneal Injections of Human Bone Marrow Mesenchymal Stem Cells on Cuprizone Model of Multiple Sclerosis
por: Marzban, Mohsen, et al.
Publicado: (2018)

Sacral Intraspinal Bronchogenic Cyst: A Case Report
por: Ko, Kwang-Seok, et al.
Publicado: (2008)

Neuroblastoma-secreted exosomes carrying miR‐375 promote osteogenic differentiation of bone-marrow mesenchymal stromal cells
por: Colletti, Marta, et al.
Publicado: (2020)

Clinical implication of FDG uptake of bone marrow on PET/CT in gastric cancer patients with surgical resection
por: Lee, Jeong Won, et al.
Publicado: (2017)

Micronucleus Test of DHU001, a Polyherbal Formula, in Bone Marrow Cells of Male ICR Mice
por: Roh, Seong-Soo, et al.
Publicado: (2009)

Bone Regeneration Using a Mixture of Silicon-Substituted Coral HA and β-TCP in a Rat Calvarial Bone Defect Model
por: Roh, Jiyeon, et al.
Publicado: (2016)

The therapeutic potential of bone marrow mesenchymal stem cells in premature ovarian failure
por: He, Yantao, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_5kka3ev3c8unr43krkiv1cspvf