Cargando…

Molecular Imaging of Hepatocellular Carcinoma Xenografts with Epidermal Growth Factor Receptor Targeted Affibody Probes

Hepatocellular carcinoma (HCC) is a highly aggressive and lethal cancer. It is typically asymptomatic at the early stage, with only 10%–20% of HCC patients being diagnosed early enough for appropriate surgical treatment. The delayed diagnosis of HCC is associated with limited treatment options and m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Ping, Yang, Xiaoyang, Qi, Shibo, Liu, Hongguang, Jiang, Han, Hoppmann, Susan, Cao, Qizhen, Chua, Mei-Sze, So, Samuel K., Cheng, Zhen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654646/ https://www.ncbi.nlm.nih.gov/pubmed/23710458 http://dx.doi.org/10.1155/2013/759057

Ejemplares similares

Novel celastrol derivatives inhibit the growth of hepatocellular carcinoma patient-derived xenografts
por: Wei, Wei, et al.
Publicado: (2014)

Fluorogen Activating Protein–Affibody Probes: Modular, No-Wash Measurement of Epidermal Growth Factor Receptors
por: Wang, Yi, et al.
Publicado: (2014)

Comparative evaluation of affibody- and antibody fragments-based CAIX imaging probes in mice bearing renal cell carcinoma xenografts
por: Garousi, Javad, et al.
Publicado: (2019)

Improved contrast of affibody-mediated imaging of HER3 expression in mouse xenograft model through co-injection of a trivalent affibody for in vivo blocking of hepatic uptake
por: Rosestedt, Maria, et al.
Publicado: (2019)

A Humanized Anti-GPC3 Antibody for Immuno-Positron Emission Tomography Imaging of Orthotopic Mouse Model of Patient-Derived Hepatocellular Carcinoma Xenografts
por: Natarajan, Arutselvan, et al.
Publicado: (2021)

Affibody-Binding Ligands
por: Barozzi, Annalisa, et al.
Publicado: (2020)

Blockade of Wnt-1 signaling leads to anti-tumor effects in hepatocellular carcinoma cells
por: Wei, Wei, et al.
Publicado: (2009)

Soluble Frizzled-7 receptor inhibits Wnt signaling and sensitizes hepatocellular carcinoma cells towards doxorubicin
por: Wei, Wei, et al.
Publicado: (2011)

Imaging of CAIX-expressing xenografts in vivo using (99m)Tc-HEHEHE-ZCAIX:1 Affibody molecule
por: HONARVAR, HADIS, et al.
Publicado: (2014)

Prokaryotic expression of antibodies and affibodies
por: Fernández, Luis Angel
Publicado: (2004)

Affibody molecules as engineered protein drugs
por: Frejd, Fredrik Y, et al.
Publicado: (2017)

Comparative Evaluation of Novel (177)Lu-Labeled PNA Probes for Affibody-Mediated PNA-Based Pretargeting
por: Tano, Hanna, et al.
Publicado: (2021)

Suppression of ATAD2 inhibits hepatocellular carcinoma progression through activation of p53- and p38-mediated apoptotic signaling
por: Lu, Wen-Jing, et al.
Publicado: (2015)

Radiosynthesis, optimization and pharmacokinetic study of the (99m)Tc-labeled human epidermal growth factor receptor 2 affibody molecule probe (99m)Tc-(HE)(3)Z(HER2:V2)
por: Hu, Xianwen, et al.
Publicado: (2023)

Evaluating the Therapeutic Efficacy of Mono- and Bivalent Affibody-Based Fusion Proteins Targeting HER3 in a Pancreatic Cancer Xenograft Model
por: Dahlsson Leitao, Charles, et al.
Publicado: (2020)

Radionuclide Therapy of HER2-Expressing Xenografts Using [(177)Lu]Lu-ABY-027 Affibody Molecule Alone and in Combination with Trastuzumab
por: Liu, Yongsheng, et al.
Publicado: (2023)

Imaging of Metastatic Cancer Cells in Sentinel Lymph Nodes using Affibody Probes and Possibility of a Theranostic Approach
por: Tsuchimochi, Makoto, et al.
Publicado: (2019)

Novel small (99m)Tc-labeled affibody molecular probe for PD-L1 receptor imaging
por: Liang, Zhigang, et al.
Publicado: (2022)

PET imaging of epidermal growth factor receptor expression in tumours using (89)Zr-labelled ZEGFR:2377 affibody molecules
por: GAROUSI, JAVAD, et al.
Publicado: (2016)

Targeting Tumor Cells Overexpressing the Human Epidermal Growth Factor Receptor 3 with Potent Drug Conjugates Based on Affibody Molecules
por: Rinne, Sara S., et al.
Publicado: (2022)

Molecular design of radiocopper-labelled Affibody molecules
por: Tolmachev, Vladimir, et al.
Publicado: (2018)

Affibody Molecules as Targeting Vectors for PET Imaging
por: Tolmachev, Vladimir, et al.
Publicado: (2020)

Antibody Arrays Identify Potential Diagnostic Markers of Hepatocellular Carcinoma
por: Sun, Hongbo, et al.
Publicado: (2008)

NDRG1 promotes growth of hepatocellular carcinoma cells by directly interacting with GSK-3β and Nur77 to prevent β-catenin degradation
por: Lu, Wen-Jing, et al.
Publicado: (2015)

Tankyrase inhibitors attenuate WNT/β-catenin signaling and inhibit growth of hepatocellular carcinoma cells
por: Ma, Li, et al.
Publicado: (2015)

3D Imaging Detection of HER2 Based in the Use of Novel Affibody-Quantum Dots Probes and Ratiometric Analysis
por: Pérez-Treviño, Perla, et al.
Publicado: (2018)

Experimental Therapy of HER2-Expressing Xenografts Using the Second-Generation HER2-Targeting Affibody Molecule (188)Re-ZHER2:41071
por: Liu, Yongsheng, et al.
Publicado: (2022)

Cellular Effects of HER3-Specific Affibody Molecules
por: Göstring, Lovisa, et al.
Publicado: (2012)

Engineering Saccharomyces cerevisiae for the production and secretion of Affibody molecules
por: Gast, Veronica, et al.
Publicado: (2022)

Generation of a novel affibody molecule targeting Chlamydia trachomatis MOMP
por: Li, Mingyang, et al.
Publicado: (2021)

Preclinical evaluation of (68)Ga-radiolabeled trimeric affibody for PDGFRβ-targeting PET imaging of hepatocellular carcinoma
por: Cai, Huawei, et al.
Publicado: (2023)

Cyclic versus Noncyclic Chelating Scaffold for (89)Zr-Labeled ZEGFR:2377 Affibody Bioconjugates Targeting Epidermal Growth Factor Receptor Overexpression
por: Summer, Dominik, et al.
Publicado: (2017)

Recombinant amyloid beta-peptide production by coexpression with an affibody ligand
por: Macao, Bertil, et al.
Publicado: (2008)

Discovery, optimization and biodistribution of an Affibody molecule for imaging of CD69
por: Persson, Jonas, et al.
Publicado: (2021)

The Impact of Glycerol on an Affibody Conformation and Its Correlation to Chemical Degradation
por: Ramm, Ingrid, et al.
Publicado: (2021)

Recent Advances on Affibody- and DARPin-Conjugated Nanomaterials in Cancer Therapy
por: Gabriele, Federica, et al.
Publicado: (2023)

Fluorescent Affibody Peptide Penetration in Glioma Margin Is Superior to Full Antibody
por: Sexton, Kristian, et al.
Publicado: (2013)

Affibody-mediated PET imaging of HER3 expression in malignant tumours
por: Rosestedt, Maria, et al.
Publicado: (2015)

17AAG-induced internalisation of HER2-specific Affibody molecules
por: Göstring, Lovisa, et al.
Publicado: (2016)

Generation of affibody molecules specific for HPV16 E7 recognition
por: Xue, Xiangyang, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_keridp2nd601f41mo2kg1aoseu