Synthesis and Characterization of Novel Unsymmetrical and Symmetrical 3-Halo- or 3-Methoxy-substituted 2-Dibenzoylamino-1,4-naphthoquinone Derivatives

Symmetrical and unsymmetrical 3-halo- or 3-methoxy- substituted 2-dibenzoylamino-1,4-naphthoquinone analogs were synthesized with an average yield of 45% via sodium hydride promoted bis-acylation of 2-amino-3-chloro-1,4-naphthoquinone, 2-amino-3-bromo-1,4-naphthoquinone and 2-amino-3-methoxy-1,4-nap...

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Autores principales: Brandy, Yakini, Brandy, Nailah, Akinboye, Emmanuel, Lewis, Malik, Mouamba, Claudia, Mack, Seshat, Butcher, Ray J., Anderson, Alan J., Bakare, Oladapo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654863/
https://www.ncbi.nlm.nih.gov/pubmed/23381023
http://dx.doi.org/10.3390/molecules18021973
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author Brandy, Yakini
Brandy, Nailah
Akinboye, Emmanuel
Lewis, Malik
Mouamba, Claudia
Mack, Seshat
Butcher, Ray J.
Anderson, Alan J.
Bakare, Oladapo
author_facet Brandy, Yakini
Brandy, Nailah
Akinboye, Emmanuel
Lewis, Malik
Mouamba, Claudia
Mack, Seshat
Butcher, Ray J.
Anderson, Alan J.
Bakare, Oladapo
author_sort Brandy, Yakini
collection PubMed
description Symmetrical and unsymmetrical 3-halo- or 3-methoxy- substituted 2-dibenzoylamino-1,4-naphthoquinone analogs were synthesized with an average yield of 45% via sodium hydride promoted bis-acylation of 2-amino-3-chloro-1,4-naphthoquinone, 2-amino-3-bromo-1,4-naphthoquinone and 2-amino-3-methoxy-1,4-naphthoquinone.
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spelling pubmed-36548632013-05-15 Synthesis and Characterization of Novel Unsymmetrical and Symmetrical 3-Halo- or 3-Methoxy-substituted 2-Dibenzoylamino-1,4-naphthoquinone Derivatives Brandy, Yakini Brandy, Nailah Akinboye, Emmanuel Lewis, Malik Mouamba, Claudia Mack, Seshat Butcher, Ray J. Anderson, Alan J. Bakare, Oladapo Molecules Article Symmetrical and unsymmetrical 3-halo- or 3-methoxy- substituted 2-dibenzoylamino-1,4-naphthoquinone analogs were synthesized with an average yield of 45% via sodium hydride promoted bis-acylation of 2-amino-3-chloro-1,4-naphthoquinone, 2-amino-3-bromo-1,4-naphthoquinone and 2-amino-3-methoxy-1,4-naphthoquinone. MDPI 2013-02-04 /pmc/articles/PMC3654863/ /pubmed/23381023 http://dx.doi.org/10.3390/molecules18021973 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Brandy, Yakini
Brandy, Nailah
Akinboye, Emmanuel
Lewis, Malik
Mouamba, Claudia
Mack, Seshat
Butcher, Ray J.
Anderson, Alan J.
Bakare, Oladapo
Synthesis and Characterization of Novel Unsymmetrical and Symmetrical 3-Halo- or 3-Methoxy-substituted 2-Dibenzoylamino-1,4-naphthoquinone Derivatives
title Synthesis and Characterization of Novel Unsymmetrical and Symmetrical 3-Halo- or 3-Methoxy-substituted 2-Dibenzoylamino-1,4-naphthoquinone Derivatives
title_full Synthesis and Characterization of Novel Unsymmetrical and Symmetrical 3-Halo- or 3-Methoxy-substituted 2-Dibenzoylamino-1,4-naphthoquinone Derivatives
title_fullStr Synthesis and Characterization of Novel Unsymmetrical and Symmetrical 3-Halo- or 3-Methoxy-substituted 2-Dibenzoylamino-1,4-naphthoquinone Derivatives
title_full_unstemmed Synthesis and Characterization of Novel Unsymmetrical and Symmetrical 3-Halo- or 3-Methoxy-substituted 2-Dibenzoylamino-1,4-naphthoquinone Derivatives
title_short Synthesis and Characterization of Novel Unsymmetrical and Symmetrical 3-Halo- or 3-Methoxy-substituted 2-Dibenzoylamino-1,4-naphthoquinone Derivatives
title_sort synthesis and characterization of novel unsymmetrical and symmetrical 3-halo- or 3-methoxy-substituted 2-dibenzoylamino-1,4-naphthoquinone derivatives
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654863/
https://www.ncbi.nlm.nih.gov/pubmed/23381023
http://dx.doi.org/10.3390/molecules18021973
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