Analysis of small-sample clinical genomics studies using multi-parameter shrinkage: application to high-throughput RNA interference screening

High-throughput (HT) RNA interference (RNAi) screens are increasingly used for reverse genetics and drug discovery. These experiments are laborious and costly, hence sample sizes are often very small. Powerful statistical techniques to detect siRNAs that potentially enhance treatment are currently l...

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Detalles Bibliográficos
Autores principales: van de Wiel, Mark A, de Menezes, Renée X, Siebring-van Olst, Ellen, van Beusechem, Victor W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654870/
https://www.ncbi.nlm.nih.gov/pubmed/23819807
http://dx.doi.org/10.1186/1755-8794-6-S2-S1

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