Cytomegalovirus Impairs the Induction of Indoleamine 2,3-Dioxygenase Mediated Antimicrobial and Immunoregulatory Effects in Human Fibroblasts

Human fibroblasts provide immunosuppressive functions that are partly mediated by the tryptophan-catabolizing enzyme indoleamine-2,3-dioxygenase (IDO). Moreover, upon stimulation with inflammatory cytokines human fibroblasts exhibit broad-spectrum antimicrobial effector functions directed against va...

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Detalles Bibliográficos
Autores principales: Heseler, Kathrin, Schmidt, Silvia K., Spekker, Katrin, Sinzger, Christian, Sorg, Rüdiger V., Quambusch, Marc, Zimmermann, Albert, Meisel, Roland, Däubener, Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654966/
https://www.ncbi.nlm.nih.gov/pubmed/23691219
http://dx.doi.org/10.1371/journal.pone.0064442

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