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Imatinib mesylate inhibits cell growth of malignant peripheral nerve sheath tumors in vitro and in vivo through suppression of PDGFR-β

BACKGROUND: Malignant peripheral nerve sheath tumors (MPNSTs) are highly aggressive and associated with poor prognosis. Basic research to develop new treatment regimens is critically needed. METHODS: The effects of imatinib mesylate on MPNSTs were examined in six human MPNST cell lines and in a xeno...

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Detalles Bibliográficos
Autores principales:	Ohishi, Jun, Aoki, Mikiko, Nabeshima, Kazuki, Suzumiya, Junji, Takeuchi, Tamotsu, Ogose, Akira, Hakozaki, Michiyuki, Yamashita, Yuichi, Iwasaki, Hiroshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654969/ https://www.ncbi.nlm.nih.gov/pubmed/23642185 http://dx.doi.org/10.1186/1471-2407-13-224

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