Independent of ErbB1 gene copy number, EGF stimulates migration but is not associated with cell proliferation in non-small cell lung cancer

BACKGROUND: Lung cancer often exhibits molecular changes, such as the overexpression of the ErbB1 gene. ErbB1 encodes epidermal growth factor receptor (EGFR), a tyrosine kinase receptor, involved mainly in cell proliferation and survival. EGFR overexpression has been associated with more aggressive...

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Detalles Bibliográficos
Autores principales: Lauand, Camila, Rezende-Teixeira, Paula, Cortez, Beatriz Araújo, Niero, Evandro Luís de Oliveira, Machado-Santelli, Gláucia Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655000/
https://www.ncbi.nlm.nih.gov/pubmed/23631593
http://dx.doi.org/10.1186/1475-2867-13-38

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