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Inhibition of TNF in the Brain Reverses Alterations in RAS Components and Attenuates Angiotensin II-Induced Hypertension

Dysfunction of brain renin-angiotensin system (RAS) components is implicated in the development of hypertension. We previously showed that angiotensin (Ang) II-induced hypertension is mediated by increased production of proinflammatory cytokines (PIC), including tumor necrosis factor (TNF), in brain...

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Detalles Bibliográficos
Autores principales: Sriramula, Srinivas, Cardinale, Jeffrey P., Francis, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655013/
https://www.ncbi.nlm.nih.gov/pubmed/23691105
http://dx.doi.org/10.1371/journal.pone.0063847